Summary of Key Points
Fluticasone propionate is a corticosteroid commonly used to manage conditions such as asthma, allergic rhinitis, and eczema. It works by reducing inflammation, which helps alleviate symptoms like swelling, itching, and breathing difficulties. Available in various forms, including inhalers, nasal sprays, and topical creams, it’s essential to follow your healthcare provider’s instructions for proper use. Always consult your doctor before making any changes to your dosage.
Names of Medication
Flonase (Fluticasone propionate)
Cutivate (Fluticasone propionate)
Flovent (Fluticasone propionate)
The ‘generic name’ refers to the chemical name of the active ingredient in the medication. In this case, the generic name is Fluticasone propionate.
Pharmacologic Category
Beclomethasone
Budesonide
Mometasone
Triamcinolone
Fluticasone Propionate Dosage
Fluticasone propionate is prescribed for a variety of conditions, and the dosage will depend on the specific condition being treated. Always follow your healthcare provider’s recommendations and consult them before making any adjustments to your dose. You can also schedule a telemedicine appointment with one of our providers for personalized advice.
Fluticasone Propionate for Asthma (Adults)
Inhaler: 88 mcg to 880 mcg twice daily. The dose may be adjusted based on the severity of your asthma. Treatment is typically long-term to help manage chronic asthma.
Fluticasone Nasal Spray for Allergic Rhinitis (Adults)
Nasal Spray: 2 sprays (50 mcg per spray) in each nostril once daily, or 1 spray in each nostril twice daily. The duration of treatment depends on the severity of your symptoms and may be seasonal or year-round.
Fluticasone Propionate for Chronic Obstructive Pulmonary Disease (COPD)
Inhaler: 250 mcg twice daily. This is usually part of a combination therapy with other medications. Treatment is generally long-term to help manage COPD symptoms.
Fluticasone Nasal Spray for Nasal Polyps
Nasal Spray: 2 sprays (50 mcg per spray) in each nostril twice daily. The duration of treatment depends on the severity of the condition and may be adjusted by your healthcare provider.
Fluticasone Propionate for Eczema, Psoriasis, Dermatitis, Urticaria
Topical Cream/Ointment: Apply a thin layer to the affected area once or twice daily. The length of treatment varies based on the severity of the skin condition. Consult your doctor if symptoms persist.
Fluticasone Nasal Spray for Allergic Conjunctivitis
Nasal Spray: 1-2 sprays (50 mcg per spray) in each nostril once daily. The duration of treatment depends on the severity of your symptoms.
Fluticasone Nasal Spray for Sinusitis
Nasal Spray: 2 sprays (50 mcg per spray) in each nostril once daily. Treatment may last several weeks, depending on the severity of the condition.
Dosage Forms and Strengths of Fluticasone Propionate
Inhaler: 44 mcg, 110 mcg, 220 mcg per actuation
Nasal Spray: 50 mcg per spray
Topical Cream: 0.05%
Topical Ointment: 0.005%
How to Use Fluticasone Propionate: Administration Instructions
Fluticasone propionate should be used exactly as prescribed by your healthcare provider. For inhalers, shake well before each use and rinse your mouth after inhalation to prevent oral infections. Nasal sprays should be primed before first use and sprayed into each nostril as directed. When applying topical forms, use a thin layer on clean, dry skin and avoid covering the area with tight bandages unless instructed by your doctor.
Contraindications for Fluticasone Propionate
A contraindication is a specific situation where a medication should not be used due to potential harm. It’s important to be aware of any conditions you may have before starting Fluticasone propionate:
- Allergy to Fluticasone propionate: If you have a known allergy to Fluticasone propionate or any of its ingredients, you should not take this medication. Allergic reactions can range from mild skin rashes to severe breathing difficulties (anaphylaxis).
- Untreated fungal, bacterial, or viral infections: Fluticasone propionate can weaken the immune system, making it harder to fight infections. If you have an untreated infection, using this medication could worsen it.
- Recent nasal surgery or injury: If you’ve had surgery or an injury to your nose, using Fluticasone propionate could slow the healing process. It’s best to wait until fully healed before using this medication.
- Active tuberculosis (TB): If you have TB, Fluticasone propionate could worsen your condition by suppressing your immune system. Always inform your healthcare provider if you have a history of TB.
Drug-to-Drug Interactions with Fluticasone Propionate
Fluticasone propionate can interact with other medications, potentially causing harmful effects or reducing the effectiveness of either drug. Be sure to inform your healthcare provider about all medications you are taking, including over-the-counter drugs and supplements. Below are some common medications that may interact with Fluticasone propionate:
- Ritonavir (Norvir): This antiviral medication used to treat HIV can increase Fluticasone propionate levels in your body, leading to more side effects.
- Ketoconazole (Nizoral): This antifungal drug can also increase Fluticasone propionate concentration, raising the risk of side effects.
- Itraconazole (Sporanox): Another antifungal medication that can raise Fluticasone propionate levels, leading to potential complications.
- Clarithromycin (Biaxin): This antibiotic may increase Fluticasone propionate in your bloodstream, heightening the risk of side effects.
Fluticasone Propionate in Pregnancy
Is it safe to take Fluticasone propionate during pregnancy?
Fluticasone propionate is classified as a Category C drug by the FDA for use during pregnancy. This means that while no well-controlled studies have been conducted in pregnant women, animal studies suggest there may be potential risks to the fetus. However, in some cases, the benefits of using Fluticasone propionate may outweigh these risks. If you are pregnant or planning to become pregnant, it’s important to consult your healthcare provider to determine whether this medication is appropriate for you. Our telemedicine providers are available to help you assess the risks and benefits based on your specific health needs.
Fluticasone Propionate While Breastfeeding
Is it safe to take Fluticasone propionate while breastfeeding?
There is limited information regarding the safety of Fluticasone propionate during breastfeeding. Small amounts of the medication may pass into breast milk, but it is unclear whether this poses any risk to a nursing infant. If you are breastfeeding, it’s essential to consult your healthcare provider before using Fluticasone propionate. Our telemedicine providers can guide you in making the best decision for both you and your baby.
Estimated Cost of Fluticasone Propionate
The cost of a 30-day supply of Fluticasone propionate without insurance can vary depending on the form (nasal spray, inhaler, or topical cream) and dosage. With a GoodRX coupon, the estimated cost for a 30-day supply of Fluticasone propionate nasal spray typically ranges from $15 to $30. Be sure to check with your pharmacy for the most accurate pricing.
Possible Alternatives to Fluticasone Propionate
If Fluticasone propionate is not suitable for you, there are alternative treatments and lifestyle changes that may help manage your condition. Always consult your healthcare provider before making any changes to your treatment plan. Our telemedicine providers are available to help you explore these options.
Asthma
Alternatives include other inhaled corticosteroids such as Budesonide (Pulmicort) or combination inhalers like Fluticasone/Salmeterol (Advair). Lifestyle changes, such as avoiding asthma triggers and maintaining a healthy weight, can also help manage symptoms.
Allergic Rhinitis
Alternatives include antihistamines like Cetirizine (Zyrtec) or Loratadine (Claritin), as well as decongestants. Nasal saline rinses and avoiding allergens can also help reduce symptoms.
Chronic Obstructive Pulmonary Disease (COPD)
Alternatives include bronchodilators such as Tiotropium (Spiriva) or combination inhalers like Fluticasone/Vilanterol (Breo). Quitting smoking and participating in pulmonary rehabilitation are essential lifestyle changes for managing COPD.
Nasal Polyps
Alternatives include oral corticosteroids or surgery in more severe cases. Nasal saline irrigation can also help manage symptoms.
Eczema
Alternatives include moisturizers, topical calcineurin inhibitors like Tacrolimus (Protopic), and phototherapy. Avoiding irritants and using gentle skincare products are important lifestyle changes to help manage eczema.
Psoriasis
Alternatives include topical treatments such as Calcipotriene (Dovonex) or systemic treatments like Methotrexate. Stress management and maintaining a healthy diet can also play a role in managing psoriasis symptoms.
Allergic Conjunctivitis
Alternatives include antihistamine eye drops like Ketotifen (Zaditor) or Olopatadine (Patanol). Avoiding allergens and using cold compresses can provide additional relief.
Sinusitis
Alternatives include nasal decongestants, saline nasal sprays, and in some cases, antibiotics. Staying hydrated and using a humidifier can also help alleviate symptoms.
Dermatitis
Alternatives include topical corticosteroids, antihistamines, and avoiding known irritants. Regular moisturizing can help manage dermatitis symptoms.
Urticaria (Hives)
Alternatives include antihistamines such as Diphenhydramine (Benadryl) or Fexofenadine (Allegra). Avoiding known triggers and wearing loose clothing can help prevent flare-ups.
Recent Updates on Fluticasone Propionate Research
Recent studies have focused on the long-term safety of Fluticasone propionate, particularly in children and individuals with chronic conditions like asthma and COPD. Research indicates that while Fluticasone propionate is effective in managing symptoms, long-term use may slightly reduce growth in children. However, this effect is generally considered minimal compared to the benefits of controlling asthma or other conditions. Ongoing studies are also exploring new formulations that may reduce side effects while maintaining the medication’s effectiveness.
It’s important to stay informed about the latest research and discuss any concerns with your healthcare provider. Our telemedicine providers are here to help you understand how new research may impact your treatment plan.
James Kingsley
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